List of all the important adverse effects of different common drugs that are usually asked in exams and also essential in our clinical practise.

Agranulocytosis Clozapine, Chloramphenical
Aplastic Anemia
  • Chloramphenicol
  • NSAIDs
  •  Benzene




Atropine-like Side Effects Tricyclics
Cardiotoxicity Doxorubicin



Cartilage Damage in Children Fluoroquinolones (Ciprofloxacin & Norfloxacin)
Cinchonism Quinidine
Cough ACE Inhibitors
Disulfiram-like Effect Metronidazole , Sulfonylureas (1st generation)
Extrapyramidal Side Effects Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine)
Fanconi’s Syndrome Tetracycline
Fatal Hepatotoxicity (necrosis) Valproic Acid, Halothane , Acetaminophen
Gingival Hyperplasia Phenytoin
Gray Baby Syndrome Chloramphenicol
Gynecomastia Cimetidine, Azoles, Spironolactone, Digitalis, Isoniazid
Hemolytic Anemia in G6PD-deficiency Sulfonamides, Isoniazid, Aspirin, Ibuprofen, Anti-malarial drugs, Dapsone
  • Anabolic steroids
  • Birth control pills
  • Chlorpromazine
  • Erythromycin
  • Halothane (a type of anesthesia)
  • Methyldopa
  • Isoniazid
  • Methotrexate
  • Statins
  • Sulfa drugs
  • Tetracyclines
  • Amoxicillin-clavulanate
  • Some anti-seizure medicines















Hot Flashes, Flushing Niacin, Tamoxifen, Ca++ Channel Blockers
Induce CP450 Barbiturates, – Phenobarbital, Phenytoin, Carbamazepine, Rifampin
Inhibit CP450 Cimetidine, Ketoconazole
Interstitial Nephritis Methicillin, NSAIDs (except Aspirin), Furosemide, Sulfonamides
Monday Disease Nitroglycerin Industrial exposure → tolerance during week → loss of tolerance during weekend → headache, –


ach, dizziness upon re-exposure

Nephrogenic Diabetes Insipidus Lithium (Txt w/ Amiloride)
Orange Body Fluids Rifampin
Osteoporosis Heparin Corticosteroids
Peptic Ulcer NSAIDS, Corticosteroids, cytotoxic drugs. But NSAIDS are protective against colonic carcinoma.
Positive Coomb’s Test Methyldopa
Pulmonary Fibrosis Bleomycin, Amiodarone
Red Man Syndrome Vancomycin
SLE-like Syndrome Hydralazine, INH, Procainamide (HIP)
Severe HTN with Tyramine MAOIs
Tardive Dyskinesia Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine) Clozapine: only antipsychotic to not give you tardive dyskinesia
Tinnitus Aspirin, Quinidine
Thrmobocytopenia Quinine, Quinidine, Vancomycin, Heparin
Megaloblastic Anemia Phenytoin, Primadone, B12 and folic acid defeciencies, Alchohol, Trimethoprim, Sulfasalazine, Metformin, Antifolates (Methotrexate), N2O



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