List of all the important adverse effects of different common drugs that are usually asked in exams and also essential in our clinical practise.
| Agranulocytosis | Clozapine, Chloramphenical |
|
Aplastic Anemia
|
|
| Atropine-like Side Effects | Tricyclics |
| Cardiotoxicity | Doxorubicin
Daunorubicin |
| Cartilage Damage in Children | Fluoroquinolones (Ciprofloxacin & Norfloxacin) |
| Cinchonism | Quinidine |
| Cough | ACE Inhibitors |
| Disulfiram-like Effect | Metronidazole , Sulfonylureas (1st generation) |
| Extrapyramidal Side Effects | Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine) |
| Fanconi’s Syndrome | Tetracycline |
| Fatal Hepatotoxicity (necrosis) | Valproic Acid, Halothane , Acetaminophen |
| Gingival Hyperplasia | Phenytoin |
| Gray Baby Syndrome | Chloramphenicol |
| Gynecomastia | Cimetidine, Azoles, Spironolactone, Digitalis, Isoniazid |
| Hemolytic Anemia in G6PD-deficiency | Sulfonamides, Isoniazid, Aspirin, Ibuprofen, Anti-malarial drugs, Dapsone |
| Hepatitis |
|
| Hot Flashes, Flushing | Niacin, Tamoxifen, Ca++ Channel Blockers |
| Induce CP450 | Barbiturates, Phenobarbital, Phenytoin, Carbamazepine, Rifampin |
| Inhibit CP450 | Cimetidine, Ketoconazole |
| Interstitial Nephritis | Methicillin, NSAIDs (except Aspirin), Furosemide, Sulfonamides |
| Monday Disease | Nitroglycerin Industrial exposure → tolerance during week → loss of tolerance during weekend → headache, –
ach, dizziness upon re-exposure |
| Nephrogenic Diabetes Insipidus | Lithium (Txt w/ Amiloride) |
| Orange Body Fluids | Rifampin |
| Osteoporosis | Heparin Corticosteroids |
| Peptic Ulcer | NSAIDS, Corticosteroids, cytotoxic drugs. But NSAIDS are protective against colonic carcinoma. |
| Positive Coomb’s Test | Methyldopa |
| Pulmonary Fibrosis | Bleomycin, Amiodarone |
| Red Man Syndrome | Vancomycin |
| SLE-like Syndrome | Hydralazine, INH, Procainamide (HIP) |
| Severe HTN with Tyramine | MAOIs |
| Tardive Dyskinesia | Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine) Clozapine: only antipsychotic to not give you tardive dyskinesia |
| Tinnitus | Aspirin, Quinidine |
| Thrmobocytopenia | Quinine, Quinidine, Vancomycin, Heparin |
| Megaloblastic Anemia | Phenytoin, Primadone, B12 and folic acid defeciencies, Alchohol, Trimethoprim, Sulfasalazine, Metformin, Antifolates (Methotrexate), N2O |
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