Vitamins play a crucial role in maintaining good health and preventing various diseases. However, excessive intake of vitamins, especially through supplements, has been a matter of concern for a long time. A recent study published in JAMA Network Open has investigated the association between high intakes of vitamins B6 and B12 and the risk of hip fracture in postmenopausal women.
The study followed 75,864 postmenopausal women in the United States for over 30 years, collecting information on hip fractures, dietary intake of vitamins B6 and B12, and a range of potential confounders. The results showed that both vitamin B6 and B12 were associated with an increased risk of hip fracture. The risk was highest in women with a combined high intake of both vitamins (B6 ≥35 mg/day and B12 ≥20 μg/day), exhibiting an almost 50% increased risk of hip fracture compared with women with a low intake of both vitamins (B6 <2 mg/day and B12 <10 μg/day).
These findings add to the growing body of evidence suggesting that excessive intake of vitamins through supplements can have adverse effects, including an increased risk of fractures. It is important to note that the intakes of vitamins B6 and B12 in this study were far higher than the recommended dietary allowances (RDA). The RDAs for vitamins B6 and B12 are 1.3-1.7 mg/day and 2.4 μg/day, respectively, for adult women.
It is always advisable to get your vitamins and nutrients from a balanced diet, rather than relying solely on supplements. Foods rich in vitamin B6 include poultry, fish, potatoes, and bananas, while vitamin B12 can be found in animal products such as meat, dairy, and eggs. If you are considering taking a vitamin supplement, it is best to consult with a healthcare professional to determine your individual needs and to avoid any potential adverse effects.
In conclusion, the study highlights the importance of careful and cautious use of vitamin supplements and the need to not exceed the recommended levels. A balanced diet can provide all the vitamins and nutrients that your body needs, and it is always best to consult with a healthcare professional before starting any supplement regimen.
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